Low Birth, Prematurity, and Pre-Eclampsia as Risk Factors of Neonatal Asphyxia
Abstract
Background: Asphyxia neonatorum is the condition of an infant who does not breathe spontaneously and regularly immediately after birth. This condition is accompanied by hypoxia, hypercapnia, and ends with acidosis. Long-standing asphyxia can cause brain damage and death. This study aimed to investigate risk factors of asphyxia in Nganjuk Hospital, East Java.
Subjects and Method: This was an analytic observational study with a case control design. The study was conducted in Nganjuk Hospital, East Java, in July 2018. A total sample of 150 neonates was selected by fixed disease sampling, consisting of 50 neonates with asphyxia and 1oo neonates without asphyxia. The dependent variable was asphyxia. The independent variables were low birth weight, preterm birth, and pre eclampsia. The data were obtained from medical record and analyzed by a multiple logistic regression.
Results: The risk of asphyxia increased with low birth weight (OR= 2.58; 95% CI = 3.80 to 46.15; p<0.001), premature birth (OR= 1.27; 95% CI= 1.23 to 10.25; p= 0.019), and pre-eclampsia (OR= 3.74; 95% CI= 12.54 to 141.05; p <0.001).
Conclusions: The risk of asphyxia increases with low birth weight, premature birth, and pre-eclampsia.
Keywords: asphyxia, neonates, low birth weight, premature, preeclampsia
Correspondence:
References
Aminah, Wahyu MS (2016). Hubungan Bayi Prematur dengan Kejadian Asfiksia Neonatorum. Jurnal Obstetrika Scientia. 4 (2)
Antonucci R, Porcella A, Pilloni MD (2014). Perinatal Asphyxia In The Term Newborn, Journal of Pediatric and Neonatal Individualized Medicine. 3(2): e030269. https://doi:10.7363/ 030269.
Aslam HM, Saleem S, Afzal R, Iqbal U, Saleem SM, Shaikh MWK, Shahid N (2014). Risk Factors of Birth Asphyxia, Italian. Journal of Pediatrics. https://bdoi.org/10.1186/s1305201400942
Cunningham FG (2016). Obstetri Williams. Jakarta: EGC
Dinkes (2012) Provinsi Jawa Timur (2012). Profil Kesehatan Provinsi Jawa Timur Tahun 2012. Dinas Kesehatan Jawa Timur
Dinas Kesehatan Kabupaten Nganjuk (2014). Profil Dinas Kesehatan Daerah Kab Nganjuk Tahun 2016
Ekwochi U, Asinobi NI, Osuorah CDI, Ndu IK, Ifediora C, Amadi OF, Iheji CC, Orjioke CJG, Okenwa WO and Okeke BI. (2017). Incidence and Predictors of Mortality Among Newborns With Perinatal Asphyxia: A 4Year Prospective Study of Newborns Delivered in Health Care Facilities in Enugu, South East Nigeria. Clinical Medicine Insights: Pediatrics, Gynecol. 118(3): 561
Ilah BG, Aminu MS, Musa A, Adelakun MB, Adeniji AO, Kolawole T (2015). Prevalence and Risk Factors for Perinatal Asphyxia as Seen at a Specialist Hospital in Gusau, Nigeria. SubSaharan Afr J Med. 2:649. Doi: 10.4103/23845147.157421
Indah SN, Apriliana E (2016). Hubungan antara Preeklamsia dalam Kehamilan dengan Kejadian Asfiksia pada Bayi Baru Lahir. Jurnal Majority. 5(5).
Jebessa Wayessa Z, Belachew T, Joseph J (2018). Birth asphyxia and associated factors among newborns delivered in Jimma zone public hospitals, Southwest Ethiopia: A cross sectional study. Journal of Midwifery and Reproductive. Health. 6(2): 12891295. doi:10.22038/JMRH.2018.10483.
Kosim MS (2014). Buku Ajar Neonatologi. Jakarta: IDAI
Manuaba IBG (2008). Gawat Darurat Obstetri Ginekologi & Obstetri Ginekologi Sosial Untuk Profesi Bidan. Jakarta: EGC
Maryunani A (2009). Asuhan Kegawatan Dan Penyulit Pada Neonatus. Jakarta: Trans Info Medika
Mohan K, Mishra PC, Singh DK. (2013). Clinical Profile of Birth Asphyxia In Newborn, International Journal of Science & Technology. 3(1). ISSN (online): 250141X
Momeni M, Danaei M, Kermani AJ, Bakhshandeh M, Foroodnia S, Mahmoudabadi Z, Amirzadeh R, Safizadeh H. (2017). Prevalence and Risk Factors of Low Birth Weight in the Southeast of Iran. International Journal of Preventive Medicine. doi:10.4103/ijpvm.IJPVM_112_16.
Muslihatun. (2010). Asuhan Neonatus, Bayi Dan Balita. Yogyakarta: Fitramaya
Prambudi R (2013). Neonatologi Praktis: Prosedur Tindakan Neonatus. Bandar. Lampung: Anugrah Utama Raharja
Rachmawati L, Ningsih MP (2015). Faktor-Faktor yang Berhubungan dengan Kejadian Asfiksia pada Bayi Baru Lahir Di Ruang Medical Record RSUD Pariaman. Jurnal Ilmiah Kebidanan. 7 (1): 29-40
Proverawati A (2010). Berat Badan Lahir Rendah. Yogyakarta: Nuha Medika
Purwaningsih Y, Dewi YLR, Indarto D, Murti B (2018). Factors Associated with Newborn Asphyxia at Dr. Harjono Hospital, Ponorogo, East Java. Journal of Maternal and Child Health. 3(4): 287-293. https://doi.org/10.26911/thejmch.2018.03.04.06
Rukiyah. (2010). Asuhan Neonatus Bayi Dan Anak Balita. Jakarta : Trans Info Medika
Wiknjosastro H (2007). Ilmu Kebidanan. Edisi Ke-4 Cetakan Ke-2. Jakarta: Yayasan Bina. Jakarta: EGC
