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Meta-Analysis: The Effects of Depression and Anxiety on the Quality of Life of People with Disability

Iffah Nurhayati, Bhisma Murti, Hanung Prasetya

Abstract

Background: A person with a disability is a person who has (suffers) a disability/ limitations in the structure and function of the body which can cause problems in their life. Environmental conditions (physical, biological and social) that are not disability-friendly will have an impact on mental problems and the most common are depression and anxiety. Depression and anxiety have an important influence on the health conditions and quality of life of persons with disabilities. The purpose of this study was to analyze the effect of depression on the quality of life of persons with disabilities and to analyze the effect of anxiety on the quality of life of persons with disabilities.

Subjects and Method: The meta-analysis was carried out by systematically reviewing the same number of articles from PubMed, Science Direct, and Google Scholar. This is done using the search keywords “anxiety” AND “depression” AND “quality of life” AND “disability” AND “multivariate analysis”. The population in this study were persons with disabilities. The interventions given were anxiety and depression, while the comparison was not anxious and not depressed. The outcome of the study was quality of life. The article used is a full text article with an observational study design that reports the value of the Adjusted Odds Ratio (aOR). Articles were collected using PRISMA flowcharts and analyzed using the Review Manager 5.3 application with random effect models.

Results: Meta-analysis in 8 cross-sectional studies of depression can reduce 0.79 times the quality of life of persons with disabilities (aOR= 0.79; 95% CI= 0.69-0.92; p= 0.002) and in 3 cohort studies depression decreased 0.61 times the quality of life of persons with disabilities (aOR= 0.61; 95% CI= 0.30-1.22; p= 0.16). Meta-ana¬lysis in 8 cross-sectional studies, anxiety decreased 0.70 times the quality of life of persons with disabilities (aOR= 0.70; 95% CI= 0.60; p<0.001) and in 5 cohort studies anxiety decreased 0.84 times (aOR= 0.84; 95% CI= 0.68-1.04; p= 0.12).

Conclusion: Depression and anxiety have an effect on decreasing the quality of life of persons with disabilities.

Keywords: Anxiety, depression, quality of life, disability, multivariate analysis

Correspondence: Iffah Nurhayati, Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: iffahn16@gmail.com. Mobile-phone: 085742202990.

Journal of Maternal and Child Health (2021), 06(03): 267-284
https://doi.org/10.26911/thejmch.2021.06.03.02

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