Premature Rupture of Membrane Outcome Determinants in Reproductive Age Women

Sarah Chairani Zakirah, Putri Chairani Eyanoer, Chairul Nurdin Azali, Budi Wiweko


Background:  Premature Rupture of Membrane (PROM) may cause maternal and neonatal mor­bi­dity and mortality. This study aimed to in­ves­ti­ga­te the risk factors related to PROM in pregnant wo­men below <35 years old.

Subjects and Method: This cross-sectional stu­dy was conducted in Kertha Usada General Hos­­­pital, North Bali, Indonesia. We collected 224 repoductive women using consecutive sampling. The dependent variable was premature rupture of membrane. The inde­pen­­dent variables were gra­vidity status, ges­ta­tio­nal age, body mass index (BMI), history of cae­sa­rean section, miscarriage, infection, and anemia. Data of infection was obtained from examination, such as neutro­phil, lymphocyte, platelet, neutrophil-to-lympho­cyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). We also obtained Hb, MCV, and MCH as laboratory parameter of ane­mia. The data were analyzed by a multiple logistic regress­ion.

Results: Multigravida (or= 0.04; 95% CI= 0.01 to 0.27; p= 0.001) and MCH >34 pg (OR= 0.10; 95% CI= 0.01 to 0.86; p= 0.036) decreased the risk of premature of rupture membrane in women of reproductive age.

Conclusion: Multigravida and MCH >34 pg decrease the risk of premature of rupture mem­brane in women of reproductive age.

Keywords: premature rupture membrane

Correspondence: Putri Chairani Eyanoer. Department Community and Preventive Medicine, Faculty of Medicine, Uni­­versitas Sumatera Utara, Medan, Indonesia. Email: Mobile: +62-813 7023-2513

Journal of Maternal and Child Health (2020), 5(4): 576-586

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