Relationship Between Pregnancy Anemia and Depression in Postpartum Mothers: Systematic Review
DOI:
https://doi.org/10.26911/thejmch.2024.09.05.10Abstract
Background: Anemia is one of the most significant global public health problems that affects a person's physical and mental abilities. Geography, lifestyle, and diet influence the prevalence of anemia in pregnant women, which is estimated to range from 14 to 80% in different countries (WHO, 2019. This study aims to analyze the relationship between pregnancy anemia and the incidence of depression in postpartum mothers.
Subjects and Method: Systematic Review using the PRISMA diagram in the RevMan 5.3 application. Database searches from PubMed, Scopus, Wiley Online Library, and Science Direct were conducted in 2022-2024, and can be accessed for free, with the search terms "Anemia in pregnancy" OR "Low level of hemoglobin in pregnancy" AND "depression".
Results: A total of 6 articles that were selected from 432 quantitative articles based on inclusion and exclusion criteria, showed that there was a significant relationship between gestational anemia and the incidence of depression in postpartum mothers. However, some articles have not shown a significant association between pregnancy anemia and postpartum depression.
Conclusion: Although there are studies that have not significant results, the administration of blood supplement tablets and monitoring of Fe intake in pregnant women for the prevention of anemia is important because there is a 50% chance of causing depression and other consequences during and after childbirth.
Keywords:
pregnancy anemia, postpartum depression laceration, systematic reviewReferences
Aoki C, Imai K, Owaki T, Kobayashi-Nakano T, Ushida T, Iitani Y, Nakamura N, et al. (2022). The Possible Effects of Zinc Supplementation on Postpartum Depression and Anemia. Medicina (Lithuania), 58(6):731. doi: 10.3390/medicina58060731.
Bombac Tavcar L, Hrobat H, Gornik L, Globevnik Velikonja, Lučovnik M. (2023). Incidence of postpartum depression after treatment of postpartum anaemia with intravenous ferric carboxymaltose, intravenous ferric de-risomaltose or oral ferrous sulphate: A randomized clinical trial. European Journal of Obstetrics and Gynecology and Reproductive Biology: X, 20(October). doi: 10.1016/j.eurox.2023.100247.
Chandrasekaran N, De Souza L R, Urquia M L, Young B, McLeod A, Windrim R, Berger H. (2018). Is anemia an independent risk factor for postpartum depression in women who have a cesarean section? - A prospective obser-vational study. BMC Pregnancy and Childbirth, 18(1):1–7. doi:10.1186/s1-2884-018-2032-6
Cheng Z, Karra M, Guo M, Patel V, Canning D. (2023). Exploring the Relation-ship between Anemia and Postpartum Depression: Evidence from Malawi. International Journal of Environmental Research and Public Health, 20(4):178. doi:10.3390/ijerph20043178
Kemppinen L, Mattila M, Ekholm E, Huolila L, Pelto J, Karlsson H, Mäkikallio K, Karlsson L. (2022). Gestational anemia and maternal antenatal and post-partum psychological distress in a prospective FinnBrain Birth Cohort Study. BMC Pregnancy and Childbirth, 22(1):1–9.doi:10.1186/s12884-022-05032-z
Kwak D W, Kim S, Lee S Y, Kim M H, Park H J, Han Y J, Cha D H, Kim M Y, Chung J H, Park B, Ryu H M. (2022). Maternal Anemia during the First Tri-mester and Its Association with Psychological Health. Nutrients, 14(17):1–13. doi:10.3390/nu14173505
La Verde M, Luciano M, Fordellone M, Brandi C, Carbone M, Di Vincenzo M, Lettieri D, Palma M, Marrapodi M M, Scalzone G, Torella M. (2024). Is there a correlation between prepartum anaemia and an increased likelihood of developing postpartum depression? A prospective observational study. Archives of Gynecology and Obstetrics, 310(2): 1099–1108. doi:10.1007/s0-0404-023-07344-7
Lahasa W A, Mutmainna A, Kasim J. (2022). The relationship between anemia and the incidence of bleeding in postpartum mothers (Hubungan anemia dengan kejadian perdarahan pada ibu postpartum). Ilmiah Mahasiswa & Penelitian Kepe-rawatan, 2(1):132–140.
Maeda Y, Ogawa K, Morisaki N, Tachibana Y, Horikawa R, Sago H. (2020). Association between perinatal anemia and postpartum depression: A prospective cohort study of Japanese women. International Journal of Gynecology and Obstetrics, 148(1):48–52.doi:10.1002/ijgo.12982
Noshiro K, Umazume T, Hattori R, Kataoka S, Yamada T, Watari H. (2022). He-moglobin Concentration during Early Pregnancy as an Accurate Predictor of Anemia during Late Pregnancy. Nutrients, 14(4):1–8. doi:10.3390/nu14040-839
Pai R D, Chong Y S, Clemente-Chua L R, Irwinda R, Huynh T N K, Wibowo N, Gamilla M C Z, Mahdy Z A. (2023). Prevention and Management of Iron Deficiency/Iron-Deficiency Anemia in Women: An Asian Expert Consensus. Nutrients, 15(14):1–14. doi:10.3390/nu15143125
Skolmowska D, Głąbska D, Kołota A, Guzek D. (2022). Effectiveness of dietary interventions in prevention and treatment of iron-deficiency anemia in pregnant women. Nutrients, 14(15):3023.
Sri W, Yustina A, Chentia M I. (2021). Hubungan Anemia Kehamilan Dengan Kejadian Berat Badan Lahir Rendah (Bblr): Systematic Literatur Review. Journal of Health (JoH), 8(2):94–104. doi:10.30590/joh.v8n2.p94-104.2021
Su J Y, Chen Y, Chen H F, Tong J R, Wei Y N, Huang L L, Deng L. (2023). Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease. European Review for Medical and Pharmacological Sciences, 27(3):1027–1032. doi:10.26355/eurrev_20-2302_31198
Sucu S T, Karaman E, Kose C, Sucu S, Keskin H L. (2024). Is postpartum depression related to total weight gain during pregnancy and maternal anemia? Revista Da Associacao Medica Brasileira, 70(2):2–6. doi:10.1590-/1806-9282.20230908
Tian Q, Chen S, Jiang D. (2022). Effects of anemia during the third trimester of pregnancy on postpartum depression and pregnancy outcomes in pregnant women older than 35 years: a retrospective cohort study. Annals of Palliative Medicine, 11(3):1048–1057. doi:10.21037/apm-22-165
Worku M G, Alamneh T S, Teshale A B, Yeshaw Y, Alem A Z, Ayalew H G, Liyew A M, Tessema Z T, Tesema G A. (2022). Multilevel analysis of determinants of anemia among young women (15-24) in sub-Sahara Africa. PLoS ONE, 17(5 May), 1–16. doi:10.1371/journal.pone.0268129
Irvana. (2021). Factors Affecting the Incidence of Postpartum Depression at Labuang Baji Makassar Hospital (Faktor-Faktor yang Mempengaruhi Kejadian Depresi Post Partum di RSUD Labuang Baji Makassar). Nursing Inside Community, 3(2), 61–66.
