The Profile of Physical Activity in Children Surviving Acute Lymphoblastic Leukemia based on the Global Physical Activity Questionnaire in Surakarta
Background: Acute lymphoblastic leukemia is one of the most common malignancies in children with the highest incidence aged 3-7 years. Management and treatments such as chemotherapy and radiotherapy have musculoskeletal and neuromuscular side effects which can significantly reduce the physical activity of leukemia patients and survivors. This study aims to determine the profile of the physical activity level of children with acute lymphoblastic leukemia as assessed by the Global Physical Activity Questionnaire (GPAQ) in Surakarta, Indonesia.
Subjects and Method: This was a study with a cross-sectional design. Children who survived acute lymphoblastic leukemia who had completed chemotherapy at Dr. Moewardi Hospital and met the inclusion criteria were included in this study. A sample of 26 patients was selected through purposive sampling. Demographic data were obtained through interviews and the profile of the patient's physical activity level was assessed using the GPAQ questionnaire. Data analysis was performed using a Pearson Correlation test with SPSS 22.0.
Results: The total sample in this study was 26 children with acute lymphoblastic leukemia. As many as 11.5% of children with acute lymphoblastic leukemia experienced decreased physical activity. There was a significant relationship between length of stay (p=0.001), age (p=0.004), gender (p=0.031), and the degree of risk of acute lymphoblastic leukemia (p=0.004) with the category of physical activity based on the GPAQ score.
Conclusion: As many as 11.5% of children with acute lymphoblastic leukemia experienced decreased physical activity. The length of time being a survivor, the degree of risk of acute lymphoblastic leukemia, the age of the survivor, and gender are risk factors for decreased physical activity in children.
Keywords: physical activity, acute lymphoblastic leukemia survivors, children
Correspondence: Dini Safitri Zahara. Department of Pediatrics, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Kolonel Sutarto Street No. 132, Surakarta, Indonesia. email: firstname.lastname@example.org Phone: 082227174192.
Journal of Maternal and Child Health (2022), 07(02): 231-237
Howard M (2008). Haematology An Illustrated Colour Text III. USA: Saunders Elsevier.
Roganovic J (2013). Acute Lymphoblastic Leukemia in Children. In: Leukemia. Rijeka: InTech. 39
Departemen Kesehatan Republik Indonesia (2009). Laporan hasil riset kesehatan dasar (RISKESDAS) Indonesia tahun 2008. Jakarta: Departemen Kesehatan Republik Indonesia.
Simioni C, Zauli G, Martelli AM, Vitale M, Milani D, Neri LM (2018). Physical training interventions for children and teenagers affected by acute lymphoblastic leukemia and related treatment impairments. Oncotarget. 9(24): 17199
Anderson TNL, Athale ACU, Barr RD (2016). Health-related quality of life in long-term survivors of acute lymphoblastic leukemia in childhood and adolescence. Qual Life Res.26 (5): 1371-1377. Doi: 10.1007/s11136-016-1462-8
Hartman A, Hop W, Takken T, Pieters R, Heuveleibrink M Van Den (2013). Motor performance and functional exercise capacity in survivors of pediatric acute lymp-hoblastic leukemia. Pediatr Blood Cancer. 60(3): 494-9. Doi: 10.1002/pbc.24-243.
Wilson CL, Gawade PL, Ness KK (2015). Impairments that Influence Physical Function among Survivors of Childhood Cancer. Children (Basel). 2(1): 1-36. Doi: 10.3390/children2010001
Marchese VG, Connolly BH, Able C, Booten AR, Bowen P, Porter BM, et al. (2013). Relationships among severity of osteonecrosis, pain, range of motion, and functional mobility in children, adolescents, and young adults with acute lymphoblastic le-kemia. Phys Ther. 8(31):341
Hung SH, Rankin A, Virji-babul N, Pritchard S, Fryer C, Campbell KL (2017). Life and health care associating physical activity levels with motor performance and physical function in childhood survivors of acute lymphoblastic leukemia. Physiother Can. 69(1): 57
WHO (2009). Global health risks: mortality and burden of disease attributable to selected major risks. World Health Organization United State of America.
Permono B (2010). Leukemia akut. In: Buku ajar hematologi onkologi anak. 3rd ed. Jakarta: IDAI.
Tanjung C, Lukito JB, Meylani PD (2014). Nutritional status and physical activity of childhood leukemia survivors. Paedriatica Indonesiana. 54(2):67
Varedi M, Lu L, Howell CR, Partin RE, Hudson MM, Pui C, et al. (2018). Peripheral neuropathy, sensory processing, and balance in survivors of acute lymphoblastic leukemia. J clin Oncol. 36(22): 2315-2322. Doi: 10.1200/JCO.2017.76.7871.