Meta-Analysis the Effect of Oral Combination Contraceptive on Hypertension and Stroke


  • Ulul Azmi Zuhaira Masters Program in Public Health, Universitas Sebelas Maret
  • Eti Poncorini Pamungkasari Faculty of Medicine, Universitas Sebelas Maret
  • Vitri Widyaningsih Faculty of Medicine, Universitas Sebelas Maret



Background: Combined oral contraceptives are a form of contraception that are considered safe and effective for some women, but this does not rule out the possibility that combined oral contraceptives contribute to adverse health effects. Several epidemiological studies have shown that oral contraceptives have adverse effects on women's health. The use of contraceptive pills containing the hormones estrogen and progesterone can cause an increase in blood pressure and also stroke if used continuously. The purpose of this study was to estimate the magnitude of the risk of using combined oral contraceptives on the incidence of hypertension and stroke with a meta-analysis study.

Subjects and Method: This research is a systematic review and meta-analysis using PRISMA flowchart diagram guidelines. The article search process was carried out between 2007-2022 using 3 databases, including Google Scholar, PubMed, and Science Direct. The keywords used in the database search were


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How to Cite

Zuhaira, U. A., Pamungkasari, E. P., & Widyaningsih, V. (2022). Meta-Analysis the Effect of Oral Combination Contraceptive on Hypertension and Stroke. Journal of Maternal and Child Health, 7(5), 520–531.